Discover the full cast of Malpractice Series 2, new lead Tom Hughes, storyline changes, and insider scoop from ITV’s intense medical drama.


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🎬 ITV's Malpractice Returns With a Bold New Direction in Series 2

The critically acclaimed ITV medical drama Malpractice is back in 2025 with its second season, delivering a pulse-pounding shift from emergency medicine to mental health care. Premiering on Sunday, May 4, 2025, on ITV1 and ITVX, the new series opens with a shocking tragedy and introduces a completely fresh perspective—and cast—to the high-stakes world of medical investigation.

Unlike its predecessor, which followed Dr. Lucinda Edwards through the ER, the new storyline dives into the complex and often overlooked world of psychiatric care, bringing with it new ethical questions and emotional depth.

🔄 What’s New in Malpractice Series 2?

This season, the drama pivots to a brand-new lead and a powerful supporting cast, while retaining key characters from the Medical Investigation Unit (MIU).

💥 Cast Changes at a Glance:

🔹 Tom Hughes steps into the spotlight as Dr. James Ford, a psychiatric registrar whose clinical choices are questioned after a patient dies under troubling circumstances.

🔹 Familiar faces Helen Behan (Dr. Norma Callahan) and Jordan Kouamé (Dr. George Adjei) return as sharp MIU investigators unraveling a web of psychological trauma and professional recklessness.

🔹 New to the team are Selin Hizli (Dr. Sophia Hernandez) and Zoë Telford (Dr. Kate McAllister), who bring fresh energy and conflict to the storyline.

🔹 Not returning is Niamh Algar (Dr. Lucinda Edwards), whose Season 1 storyline has concluded.

🎭 Full Cast of Malpractice Season 2:

  • Tom Hughes as Dr. James Ford

  • Selin Hizli as Dr. Sophia Hernandez

  • Zoë Telford as Dr. Kate McAllister

  • Helen Behan as Dr. Norma Callahan

  • Jordan Kouamé as Dr. George Adjei

  • Hannah McClean as Rosie Newman

  • Seraphina Beh as Toni Campbell-Brown

  • Rick Warden as Eric Sawers

  • Ace Bhatti as Dr. Arun Mansoor

  • Jessica Layde as Bernadette

  • Tobi Bakare as Kwame

This diverse and dynamic cast brings gravitas and intensity to a season packed with emotional and medical complexity.

📖 What Happens in Season 2? (Spoiler-Free!)

The story begins with a disturbing event: Rosie Newman, a young mother suffering from postpartum psychosis, dies soon after being released from psychiatric care. All eyes fall on Dr. James Ford, who assessed her.

As the MIU team investigates, they uncover institutional failures, blurred boundaries, and disturbing truths hidden within hospital walls. With pressure mounting and reputations at risk, the show unravels both personal and professional consequences.

The setting may have changed, but Malpractice remains a searing look at the pressures doctors face—and the cost of getting it wrong.

🎥 Behind the Scenes

✨ The show’s creator, Grace Ofori-Attah, is a former NHS psychiatrist, lending real-world accuracy to the mental health narratives. The second series was filmed in Belfast, standing in for the fictional North Yorkshire hospital, and uses a darker, more introspective tone.

Expect bold cinematography, intense close-ups, and scenes that capture the psychological strain of healthcare professionals trying to do the right thing in impossible situations.

FAQ

No, Niamh Algar does not return for Season 2. The story has moved on from her character, Dr. Lucinda Edwards.

Tom Hughes stars as Dr. James Ford, the new central character navigating psychiatric crises.

Dr. Edwards’ storyline concluded in Season 1. The second season introduces a completely new case.

You can catch it on ITV1 every Sunday or stream episodes on ITVX.

While it draws from real medical challenges, the story is fictional. Creator Grace Ofori-Attah uses her experience as a psychiatrist for realism.

Season 2 focuses on psychiatric care, exploring ethical dilemmas in mental health treatment and doctor accountability.

Most scenes were shot in Belfast, but sets were designed to replicate a modern psychiatric facility.

ITV has not officially confirmed a third season yet, but fan interest and ratings could drive a renewal.

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