🎬 ITV's Malpractice Returns With a Bold New Direction in Series 2
The critically acclaimed ITV medical drama Malpractice is back in 2025 with its second season, delivering a pulse-pounding shift from emergency medicine to mental health care. Premiering on Sunday, May 4, 2025, on ITV1 and ITVX, the new series opens with a shocking tragedy and introduces a completely fresh perspective—and cast—to the high-stakes world of medical investigation.
Unlike its predecessor, which followed Dr. Lucinda Edwards through the ER, the new storyline dives into the complex and often overlooked world of psychiatric care, bringing with it new ethical questions and emotional depth.
🔄 What’s New in Malpractice Series 2?
This season, the drama pivots to a brand-new lead and a powerful supporting cast, while retaining key characters from the Medical Investigation Unit (MIU).
💥 Cast Changes at a Glance:
🔹 Tom Hughes steps into the spotlight as Dr. James Ford, a psychiatric registrar whose clinical choices are questioned after a patient dies under troubling circumstances.
🔹 Familiar faces Helen Behan (Dr. Norma Callahan) and Jordan Kouamé (Dr. George Adjei) return as sharp MIU investigators unraveling a web of psychological trauma and professional recklessness.
🔹 New to the team are Selin Hizli (Dr. Sophia Hernandez) and Zoë Telford (Dr. Kate McAllister), who bring fresh energy and conflict to the storyline.
🔹 Not returning is Niamh Algar (Dr. Lucinda Edwards), whose Season 1 storyline has concluded.
🎭 Full Cast of Malpractice Season 2:
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Tom Hughes as Dr. James Ford
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Selin Hizli as Dr. Sophia Hernandez
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Zoë Telford as Dr. Kate McAllister
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Helen Behan as Dr. Norma Callahan
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Jordan Kouamé as Dr. George Adjei
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Hannah McClean as Rosie Newman
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Seraphina Beh as Toni Campbell-Brown
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Rick Warden as Eric Sawers
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Ace Bhatti as Dr. Arun Mansoor
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Jessica Layde as Bernadette
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Tobi Bakare as Kwame
This diverse and dynamic cast brings gravitas and intensity to a season packed with emotional and medical complexity.
📖 What Happens in Season 2? (Spoiler-Free!)
The story begins with a disturbing event: Rosie Newman, a young mother suffering from postpartum psychosis, dies soon after being released from psychiatric care. All eyes fall on Dr. James Ford, who assessed her.
As the MIU team investigates, they uncover institutional failures, blurred boundaries, and disturbing truths hidden within hospital walls. With pressure mounting and reputations at risk, the show unravels both personal and professional consequences.
The setting may have changed, but Malpractice remains a searing look at the pressures doctors face—and the cost of getting it wrong.
🎥 Behind the Scenes
✨ The show’s creator, Grace Ofori-Attah, is a former NHS psychiatrist, lending real-world accuracy to the mental health narratives. The second series was filmed in Belfast, standing in for the fictional North Yorkshire hospital, and uses a darker, more introspective tone.
Expect bold cinematography, intense close-ups, and scenes that capture the psychological strain of healthcare professionals trying to do the right thing in impossible situations.